ASTP/ONC’s HTI-4 final rule finalizes certain proposals from the HTI-2 Patient Engagement, Information Sharing, and Public Health Interoperability proposed rule, including new and updated health IT certification criteria for electronic prior authorization, electronic prescribing, and real-time prescription benefit information. The HTI-4 final rule also includes several related criteria for application programming interface (API) functionality and finalizes the adoption of additional standards for HHS that support the exchange of clinical and administrative information with payers. HTI-4 is published as part of the FY2026 CMS Hospital Inpatient Prospective Payment System (IPPS) final rule (CMS-1833-F).
The final rule is effective on October 1, 2025.
Blog Post on the Final Rule
Fact Sheet on the Final Rule
Information Session
ASTP/ONC will host an information session to explain the final rule on Tuesday August 12, 2025 at 1pm ET. The session will be recorded.
HTI-2 Proposed Rule
Looking for content and materials from the HTI-2 proposed rule? View archived content.